CURRICULUM VITAE

Dati personali

Personal Information

Name: Alessia

E-mail: alessiacalzolari@gmail.com

Nationality: Italian

Education and training

03/2004-03/2007

PhD in “Biochemical studies of the proteome”, University “Cattolica del Sacro Cuore”, Rome.

Thesis title: “Transferrin receptor 2 localizes in lipid raft domains and is released in exosomes to activate signal transduction along the MAPK pathway”. Supervisors: Prof. Massimo Castagnola, Dr. Ugo Testa

February 2002

Laurea Degree in Chemistry – Biochemistry specialization (110/110 marks), University “La Sapienza”, Rome.

Thesis title: “Structural studies on chimeric oligonucleotides”. Supervisors: Dr. Luciano Cellai, Prof. Mario Brufani

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High school Diploma (Maturità Linguistica) (60/60 marks), “Maria Ausiliatrice” Institute, Rome.

Work experience

2003-current

Research scientist, Hematology Oncology and Molecular Medicine Department, Istituto Superiore di Sanità, Rome.

Aim of research: expression analysis and functional characterization of Transferrin Receptor 2 in human cancer cell lines and Glioblastoma tissue samples. During this period, I gained excellent scientific-writing skills, participating by first hand in the publication of several scientific papers on international journals.

2001

Visiting student, Max Planck Institute for Biochemistry, Martinsried, Munich, Germany.

Aim of research: synthesis, purification and EPR analysis of chimeric oligonucleotides as a model for the study of HIV reverse transcriptase.

2000-2001

Thesis training, CNR, Rome

Personal skills and competencies

Languages

Excellent knowledge of English and French

Social skills and competencies

Team spirit; good communication skills

Organisational skills and competencies

Working in teams, also distributed across different research centres; experienced at project based research work, including direction of junior staff; sense of organisation

Technical skills and competencies

Solid experience in techniques of molecular and cellular biology. Extensive experience in scientific writing, gained through the authoring of scientific publications, reviews, abstracts and posters

Computer skills and competencies

Experienced user of computer, including Microsoft Office (Word, Excel, Powerpoint), Internet

Workshop and Congress

Calzolari A., Deaglio S., Raggi C., Sposi N.M., Stafsnes M., Sargiacomo M., Malavasi F., Peschle C., Testa U. Transferrin receptor 2 is localized in caveolar domains in HepG2 cells and activates signal transduction along the MAPK pathway. First Congress of the International BioIron Society, 22-26 maggio 2005, Praga, Repubblica Ceca

Calzolari A., Deaglio S., Raggi C., Sargiacomo M., Sposi N.M., Malavasi F., Peschle C., Testa U. Transferrin receptor 2 is localized in caveolar domains in HepG2 cells: possible implications for signal transduction. European Iron Club, 8-11 settembre 2004, Rennes, Francia

Cianetti L., Segnalini P., Calzolari A., Morsilli O., Felicetti F., Gabbianelli M., Galbiati G., Testa U., Sposi N.M. FPN1 alternative transcripts are expressed during erythroid differentiation. European Iron Club, 8-11 settembre 2004, Rennes, Francia

Sposi N.M., Segnalini P., Calzolari A., Galbiati G., Felicetti F., Testa U., Cianetti L. An IRP-1 additional transcript is essential in human gamma-delta T cell leukemias. European Iron Club, 8-11 settembre 2004, Rennes, Francia

Publications

Calzolari A., Larocca LM, Deaglio S. et al. Transferrin receptor 2 is frequently and highly expressed in glioblastomas. Submitted to Oncogene
Calzolari A., Finisguerra V., Oliviero I. et al. Regulation of transferrin receptor 2 in human cancer cell lines. Blood Cells Mol. Dis. (2009) 42, 5-13
Calzolari A., Oliviero I., Deaglio S. et al. Transferrin receptor 2 is frequently expressed in human cancer cell lines. Blood Cells Mol. Dis. (2007) 39, 82-9
Calzolari A., Oliviero I., Testa U. Transferrin receptor 2 is emerging as a major player in the control of iron metabolism. Central European Journal of Biology (2007) 2, 34-55
Calzolari A., Raggi C., Deaglio S., Sposi N.M., Stafsnes M., Fecchi K., Parolini I., Malavasi F., Peschle C., Sargiacomo M., Testa U. TfR2 localizes in lipid raft domains and is released in exosomes to activate signal transduction along the MAPK pathway. J. Cell Sci. (2006) 119, 4486-2298
Riccioni R., Calzolari A., Biffoni M., Senese M., Riti V., Petrucci E., Pasquini L., Cedrone M., Lo-Coco F., Diverio D., Foa R., Peschle C., Testa U. Podocalyxin is expressed in normal and leukemic monocytes. Blood Cells Mol. Dis. (2006) 37, 218-225
Cianetti L., Segnalini P., Calzolari A., Morsilli O., Felicetti F., Ramoni C., Gabbianelli M., Testa U., Sposi N.M. Expression of alternative transcripts of ferroportin-1 during human erythroid differentiation. Haematologica (2005) 90, 1595-1606
Calzolari A., Deaglio S., Sposi N.M., Petrucci E., Morsilli O., Gabbianelli M., Malavasi F., Peschle C., Testa U. Transferrin receptor 2 is not expressed in normal erythroid cells. Biochem. J. (2004) 381, 629-634